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Tylenol/Crocin, Liver failure, Alcohol, Medication interactions

Fever fights infection. In all species and humans fever is the First line of defence and lowering fever increases mortality.

Frustrating to see how marketing is used to blitz the people of the devloping world from the famous brand names of the corporate world. Be it sugar laden Coke or liver toxic Tylenol/Crocin.

We travelled to Sri Lanka for the first time this winter. it was lovely.
It was sad to see that almost every small shop in the marketplace had a sign selling Crocin. The technique is also rampant in India. The brand du jour pays for the sign and the small shop gets to also display their own name.

Crocin is Tylenol in N America. Acetaminophen and paracetamol are other names. It is sold worldwide.

This commonly used drug is toxic especially when combined with other drugs or alcohol. It's toxicity has been underestimated. Unfortunately most people, doctors being no exception, just assume it is safe and that it can be taken with impunity. The truth is acetaminophen would never be approved by the FDA in the 21 st century.

Few years ago, 4 grams per day was listed in every hospitalized patient s  chart as the safe daily upper limit. Concern of liver toxicity was the reason. Then a few years ago the maximum daily dose in hospital was reduced to 2 grams per day. The maximum dosage is confusing. Read the FDA advisory here. FDA also wants to get rid of Extra Strength 500 mg pills and limit largest Crocin/Tylenol to 325mg. The seller however likes to sell more!

There is real concern for liver toxicity if patients take doses just slightly more than recommended or for more than just a few days. Chronic use depletes glutathione in the liver, essential to our liver's detoxification system.

Adding alcohol to chronic use makes Tylenol much more dangerous. Few know this. Just 2-3 drinks and some Tylenol for a headache could kill you. Destroy your liver.

Besides alcohol other interactions with medications are also dangerous. Thus statins which millions take for cholesterol phobia, the Azoles taken for candida and other fungal infections, and the hidden Tylenol in many pain and fever and sleep aids all make Tylenol the most dangerous liver destroyer for humanity. The numbers are astounding.

Tylenol and asthma is associated!

I avoid Tylenol or limit it to 1 gram a day, never more than 7 days.

And never for fever.
On importance of fever more next week.


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